TOXICOLOGY PROGRAMME COURSE DESCRIPTION

Code	Name of the Course Unit	Semester	In-Class Hours (T+P)	Credit	ECTS Credit
OYP212	TOXICOLOGY	3	3	3	5

GENERAL INFORMATION
Language of Instruction :	Turkish
Level of the Course Unit :	ASSOCIATE DEGREE, TYY: + 5.Level, EQF-LLL: 5.Level, QF-EHEA: Short Cycle
Type of the Course :	Elective
Mode of Delivery of the Course Unit	-
Coordinator of the Course Unit	Assist.Prof. İLKSEN SARI O
Instructor(s) of the Course Unit
Course Prerequisite	No

OBJECTIVES AND CONTENTS
Objectives of the Course Unit:	The aim of this course is to give information about the concept of poison and toxic dose, routes of poisons into the body, toxicoquine of poisons, toxicodynamics, individual factors affecting toxicity, systemic toxicology, risk assessment in chemicals, mechanisms of drug adverse effects and risk management in medicine
Contents of the Course Unit:	Basic Principles of Toxicology, Dose, Toxic dose, LD50, Routes of Poisons into the Body, Distribution and Excretion, Biotransformation, The Factors Affecting Biotransformation, Pharmacogenomic, Toxicogenomic Poisons, Mechanisms of action of toxicogenomic poisons, Mutajenesis Carcinogenesis Theratogenesis, Direct Effects on Tissues, Allergic Reactions, Toxicology in drug development/ clinical research, Assessment of Test Results in Toxicology and Risk Evaluation , Systemic Toxicology, Toxic Effects of Mycotoxins, Metal Toxicity, Toxic Effects of Organic Solvents, Herbal, Animal and Herbal Toxins- Effects

KEY LEARNING OUTCOMES OF THE COURSE UNIT (On successful completion of this course unit, students/learners will or will be able to)
Identifies Toxicology
Describes Parts of Toxicology
Identifies Toxic Substance (Poison)
Classifies mechanisms of toxic effects.
Resolves the toxic effects that drugs can cause.
Resolves the toxic effects that drugs can cause.

WEEKLY COURSE CONTENTS AND STUDY MATERIALS FOR PRELIMINARY & FURTHER STUDY
Week	Preparatory	Topics(Subjects)	Method
1	-	General Information about Toxicology and Poisons, Branches of Toxicology	-
2	-	Entry Route of Poisons, Absorption, Distribution, Metabolism and Excretions	-
3	-	Mechanisms of toxic effect	-
4	-	Introduction to Genetic Toxicology, Chemical Carcinogenesis	-
5	-	Theratogenesis, Chemical Carcinogenesis	-
6	-	Introduction to Systemic Toxicology, Central Nervous System Poisons. Liver Poisons.	-
7	-	Introduction to Systemic Toxicology, Central Nervous System Poisons. Liver Poisons.	-
8	-	MID-TERM EXAM	-
9	-	General Overview	-
10	-	Kidney poisons	-
11	-	Immunotoxicology	-
12	-	Immunotoxicology	-
13	-	Drug toxicity	-
14	-	Important Toxic Substances and Pesticides Around	-
15	-	Important Toxic Substances Used in Industry. Natural Origin Poisons. (Vegetable and Animal Poisons)	-
16	-	FINAL EXAM	-
17	-	FINAL EXAM	-

SOURCE MATERIALS & RECOMMENDED READING

ASSESSMENT
Assessment & Grading of In-Term Activities	Number of Activities	Degree of Contribution (%)	Description

Level of Contribution
0	1	2	3	4	5

KNOWLEDGE
Theoretical
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Temel, klinik tıp bilimleri ve adli tıp hakkında yeterli birikim sahibi olmak adli tıp alanında teorik ve pratik bilgiyi kullanma yeteneğini sağlar.					4
2	Uygun yöntem ile teknikleri seçerek ve uygulayarak, adli tıp ve otopsi işlemlerinde karşılaşılabilecek problemleri tanımlama, çözme ve postmortem örnek alma yeteneğini sağlar.	0
3	Otopsi yapım tekniklerini uygulama becerisine sahip olmak ve modern görüntüleme tekniklerini kullanabilmek, gerekli olan ekipmanları seçme yeteneğini sağlar			2
4	Otopsiyi gerçekleştirme ve otopsi sonucunda ölüm nedenini belirleme konusunda neticeye ulaşma yeteneğini sağlar.		1
5	Türkçe ve İngilizceyle yeterli şekilde kendini ifade etme yeteneğine sahip olmak, belirli konularda iletişim ve topluluk önünde fikirlerini belirtmek için özgüven ve mesleki yeterlilik yeteneğini sağlar.	0
6	Hayat boyu yeni şeyler öğrenme gerekliliği bilinci, teknoloji ve kendini yenileme yeteneği ile olur.	0

KNOWLEDGE
Factual
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Otopsi yaparken ihtiyaç duyulan malzemeleri temin etme ve pratik olarak modern teçhizatlarla otopsi işlemini uygulama yeteneğini sağlar.		1
2	Bilgilere erişme ve bu amaca göre gerekli kaynak araştırması yapmak, bilgi kaynaklarının kullanılması yeteneğini sağlar.	0

SKILLS
Cognitive
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Alanında edindiği temel düzeydeki bilgi ve becerileri kullanarak verileri yorumlar ve değerlendirir, sorunları tanımlar, analiz eder ve çözüm için planlanan çalışmalarda yer alır/sorumluluk alır.		1

SKILLS
Practical
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1		0
2		0

OCCUPATIONAL
Autonomy & Responsibility
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1		0
2		0

OCCUPATIONAL
Learning to Learn
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1			1
2		0
3					3

OCCUPATIONAL
Communication & Social
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1			1
2			1
3				2
4		0
5		0
6				2

OCCUPATIONAL
Occupational and/or Vocational
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1			1
2			1
3				2
4			1
5							5
6							5
7							5

WORKLOAD & ECTS CREDITS OF THE COURSE UNIT
Workload for Learning & Teaching Activities
Type of the Learning Activites	Learning Activities (# of week)	Duration (hours, h)	Workload (h)
Lecture & In-Class Activities	14	3	42
Preliminary & Further Study	16	4	64
Land Surveying	0	0	0
Group Work	0	0	0
Laboratory	12	2	24
Reading	0	0	0
Assignment (Homework)	0	0	0
Project Work	0	0	0
Seminar	0	0	0
Internship	0	0	0
Technical Visit	0	0	0
Web Based Learning	0	0	0
Implementation/Application/Practice	0	0	0
Practice at a workplace	0	0	0
Occupational Activity	0	0	0
Social Activity	0	0	0
Thesis Work	0	0	0
Field Study	0	0	0
Report Writing	0	0	0
Final Exam	1	1	1
Preparation for the Final Exam	0	0	0
Mid-Term Exam	0	0	0
Preparation for the Mid-Term Exam	0	0	0
Short Exam	0	0	0
Preparation for the Short Exam	0	0	0
TOTAL	43	0	131