NUTRITIONAL BIOCHEMISTRY I PROGRAMME COURSE DESCRIPTION

Code	Name of the Course Unit	Semester	In-Class Hours (T+P)	Credit	ECTS Credit
BEY207E	NUTRITIONAL BIOCHEMISTRY I	3	3	3	4

GENERAL INFORMATION
Language of Instruction :	English
Level of the Course Unit :	BACHELOR'S DEGREE, TYY: + 6.Level, EQF-LLL: 6.Level, QF-EHEA: First Cycle
Type of the Course :	Compulsory
Mode of Delivery of the Course Unit	-
Coordinator of the Course Unit	Assist.Prof. HATİCE MERVE BAYRAM
Instructor(s) of the Course Unit	Lecturer EDA MERVE KURTULUŞ
Course Prerequisite	No

OBJECTIVES AND CONTENTS
Objectives of the Course Unit:	It's aimed to gain knowledge about nutrient and energy requirements in humans, recommended daily nutritional expenditure shares, Basic energy sources (Fats, Carbohydrates, Proteins), Metabolism in good nutrition status (Liver, Fat tissue, Skeletal muscle, Brain), Metabolism in starvation (Liver, Fat tissue, Skeletal muscle, In the brain, the biomedical importance of vitamins and minerals, nutrition and coronary artery disease, cancer, obesity, such as the relationship between some diseases, nutritional disorders with changes in biochemical parameters.
Contents of the Course Unit:	MMetabolism, Production and storage of metabolic energy, Bioenergetics, Transport in Membranes, Glycolysis (Embden-Meyerhof Road), Citric acid (Krebs) cycle, Electron Transport System and Oxidative phosphorylation, Pentosphosphate pathway, Glycogenogenesis, Glycogen metabolism; glycogenesis and glycogenolysis, Lipid metabolism; fatty acid oxidation, biosynthesis, membrane lipids, cholesterol and sterol metabolism, Amino acid metabolism, Integrity of metabolism, control of metabolic processes

KEY LEARNING OUTCOMES OF THE COURSE UNIT (On successful completion of this course unit, students/learners will or will be able to)
Define the regulation of glycolytic pathway and glucose metabolism as an energy source.
Associate disorders relating to carbohydrate metabolism.
Define biochemical pathways relevant in nutrient metabolism.
Solve the causes, mechanisms and effects of diseases by using metabolism information.
Classify biomolecules.
Explain the structure and functions of biomolecules
Explain the metabolic phenomena that occur during digestion of nutrients and destruction of biomolecules.
Explain control mechanisms of metabolic pathways.
Explain amino acid metabolism.

WEEKLY COURSE CONTENTS AND STUDY MATERIALS FOR PRELIMINARY & FURTHER STUDY
Week	Preparatory	Topics(Subjects)	Method
1	Literature review, individual research	Introduction to nutrition biochemistry	Lecture, Disussion
2	Literature review, individual research	Principles of nutrition biochemistry	Lecture, Disussion
3	Literature review, individual research	Introduction to metabolism; anabolism, catabolism, intermediate metabolism, macro metabolism, types of metabolic pathways, bioenergetics, general control mechanisms in metabolism	Lecture, Disussion
4	Literature review, individual research	Introduction to metabolism; anabolism, catabolism, intermediate metabolism, macro metabolism, types of metabolic pathways, bioenergetics, general control mechanisms in metabolism	Lecture, Disussion
5	Literature review, individual research	Protein and amino acid metabolism: Nitrogen fixation and balance, digestion, absorption and degradation of proteins, General amino acid reactions: deamination, transamination, decarboxylation, elimination, urea cycle and catabolism of amino acids Deamination of amino acids	Lecture, Disussion
6	Literature review, individual research	Protein and amino acid metabolism: Nitrogen fixation and balance, digestion, absorption and degradation of proteins, General amino acid reactions: deamination, transamination, decarboxylation, elimination, urea cycle and catabolism of amino acids Deamination of amino acids	Lecture, Disussion
7	Literature review, individual research	Protein and amino acid metabolism: Amino acid biosynthesis, nitric oxide, polyamines, creatine and creatinine, biogenic amines, catecholamines, neurotransmitters etc. synthesis, Both synthesis and degradation, amino acid metabolic diseases	Lecture, Disussion
8	-	MID-TERM EXAM	-
9	Literature review, individual research	Protein and amino acid metabolism: Amino acid biosynthesis, nitric oxide, polyamines, creatine and creatinine, biogenic amines, catecholamines, neurotransmitters etc. synthesis, Both synthesis and degradation, amino acid metabolic diseases	Lecture, Disussion
10	Literature review, individual research	Glycogen metabolism: Glycogen structure and physiological importance, glucose homeostasis, glycogenesis and glycogenolysis, regulation, glycogen storage diseases Anaerobic Glycolysis (Continued)	Lecture, Disussion
11	Literature review, individual research	Glycogen metabolism: Glycogen structure and physiological importance, glucose homeostasis, glycogenesis and glycogenolysis, regulation, glycogen storage diseases Anaerobic Glycolysis (Continued)	Lecture, Disussion
12	Literature review, individual research	Oxidative decarboxylation and citrate cycle, regulation, glyoxylate cycle	Lecture, Disussion
13	Literature review, individual research	Carbohydrate metabolism; digestion / absorption, glycolysis / aerobic / anaerobic), glycogenogenesis, regulation, Cori cycle, fermentation	Lecture, Disussion
14	Literature review, individual research	Carbohydrate metabolism; Pentoz phosphate pathway: oxidative and non-oxidative reactions, regulation and Calvin cycle Anaerobic Glycolysis	Lecture, Disussion
15	Literature review, individual research	Carbohydrate metabolism; Pentoz phosphate pathway: oxidative and non-oxidative reactions, regulation and Calvin cycle Anaerobic Glycolysis	Lecture, Disussion
16	-	FINAL EXAM	-
17	-	FINAL EXAM	-

SOURCE MATERIALS & RECOMMENDED READING
Harvey R., Champe P.C., (2011). Lippincotts Illustrated Reviews Biochemistry 5th edition.
Pandey, P., & Sanjeevi, S. (Eds.). (2019). Biochemistry in nutrition. Retrieved from https://search.proquest.com.
Konukoğlu, D. (2017). Temel ve Klinik Biyokimya : Sağlık Hizmetleri Fakültesi ve Sağlık Hizmetleri Meslek Yüksekokulları için. Nobel Tıp Kitapevi.

ASSESSMENT
Assessment & Grading of In-Term Activities	Number of Activities	Degree of Contribution (%)	Description

Level of Contribution
0	1	2	3	4	5

KNOWLEDGE
Theoretical
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Assess the knowledge of all disciplines that examine the relationship between humans, the environment and food and form the basis of nutrition and dietetic practice.						5
2	Define current knowledge and practices in the field of Nutrition and Dietetics.				3

KNOWLEDGE
Factual
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Use up-to-date technological resources in the process of obtaining and providing information in the field of Nutrition and Dietetics.				3

SKILLS
Cognitive
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Assess general health problems related to nutrition.				3
2	Explain the Nutrition and Dietetics practices by using knowledge in this field.			2

SKILLS
Practical
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Apply legal and ethical principles in the use of knowledge in the field of Nutrition and Dietetics.				3

OCCUPATIONAL
Autonomy & Responsibility
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Apply knowledge and skills in the field of Nutrition and Dietetics.				3
2	Follow the plans, policies, laws, regulations and legislations that affect the dietitian profession.			2

OCCUPATIONAL
Learning to Learn
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Evaluate the knowledge about Nutrition and Dietetics with a critical perspective.						5

OCCUPATIONAL
Communication & Social
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Follow new developments in the field of Nutrition and Dietetics with sufficient foreign language knowledge.			2
2	Communicate effective verbal and written interaction between individuals.			2

OCCUPATIONAL
Occupational and/or Vocational
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Evaluate the factors affecting the food quality of the individual and society in the production-consumption chain.	0
2	Respond to patients' health, social and environmental problems.	0
3	Evaluate the nutritional status of the patients.	0
4	Interpret the clinical findings of the patients in terms of nutrition.	0
5	Plan patients-specific nutritional treatments.	0

WORKLOAD & ECTS CREDITS OF THE COURSE UNIT
Workload for Learning & Teaching Activities
Type of the Learning Activites	Learning Activities (# of week)	Duration (hours, h)	Workload (h)
Lecture & In-Class Activities	14	3	42
Preliminary & Further Study	0	0	0
Land Surveying	0	0	0
Group Work	0	0	0
Laboratory	0	0	0
Reading	14	2	28
Assignment (Homework)	0	0	0
Project Work	0	0	0
Seminar	0	0	0
Internship	0	0	0
Technical Visit	0	0	0
Web Based Learning	0	0	0
Implementation/Application/Practice	0	0	0
Practice at a workplace	0	0	0
Occupational Activity	0	0	0
Social Activity	0	0	0
Thesis Work	0	0	0
Field Study	0	0	0
Report Writing	0	0	0
Final Exam	1	1	1
Preparation for the Final Exam	1	20	20
Mid-Term Exam	1	1	1
Preparation for the Mid-Term Exam	1	10	10
Short Exam	0	0	0
Preparation for the Short Exam	0	0	0
TOTAL	32	0	102