CLINICAL BIOCHEMISTRY PROGRAMME COURSE DESCRIPTION

Code	Name of the Course Unit	Semester	In-Class Hours (T+P)	Credit	ECTS Credit
TLP207	CLINICAL BIOCHEMISTRY	3	4	3	4

GENERAL INFORMATION
Language of Instruction :	Turkish
Level of the Course Unit :	ASSOCIATE DEGREE, TYY: + 5.Level, EQF-LLL: 5.Level, QF-EHEA: Short Cycle
Type of the Course :	Elective
Mode of Delivery of the Course Unit	-
Coordinator of the Course Unit	Assist.Prof. ARZU ÖZGEN
Instructor(s) of the Course Unit	Assist.Prof. ARZU ÖZGEN
Course Prerequisite	No

OBJECTIVES AND CONTENTS
Objectives of the Course Unit:	It is aimed to define the relationship of basic biochemistry and metabolism information with diseases as clinical biochemistry, to understand the relationship of metabolites in metabolism with diseases, to determine these metabolites with the appropriate method and to teach the reference laboratory methods used in order to achieve these goals.
Contents of the Course Unit:	Protein metabolism and pathologies, Hemoglobin synthesis disorders, Porphyrias, Carbohydrate metabolism disorders, Diabetes, Lipoprotein metabolism disorders, Atherosclerosis, Lipid metabolism disorders, Lipidoses, Integration of Metabolism, Metabolism in fasting and satiety, Clinical enzymology and Marker enzymes are examined.

KEY LEARNING OUTCOMES OF THE COURSE UNIT (On successful completion of this course unit, students/learners will or will be able to)
Students can establish the relationship between basic biochemistry structure and metabolic pathways.
Students can apply sampling methods in the clinical laboratory.
Students know clinical laboratory equipment and methods.
Students will be able to determine the parameters within the scope of clinical biochemistry in the differential diagnosis of diseases affecting living organisms with the appropriate method and report the results.

WEEKLY COURSE CONTENTS AND STUDY MATERIALS FOR PRELIMINARY & FURTHER STUDY
Week	Preparatory	Topics(Subjects)	Method
1	-	Clinical Biochemistry, Definition and Preanalytics (Preparation for Sampling and Analysis)	Laboratory applications, Lecture, question and answer
2	Literature review, homework	Devices Used in Clinical Biochemistry Laboratory and Their Features	Laboratory applications, Lecture, question and answer
3	Literature review, homework	Fundamentals of Clinical Biochemistry: Blood Collection, Biochemical Analysis, Metabolism Analysis, Protein Tests	Laboratory applications, Lecture, question and answer
4	Literature review, homework	Fundamentals of Clinical Biochemistry: Blood Collection, Biochemical Analysis, Metabolism Analysis, Enzyme Analysis	Laboratory applications, Lecture, question and answer
5	Literature review, homework	Fundamentals of Clinical Biochemistry: Blood Collection, Biochemical Analysis, Metabolism Analysis, Carbohydrate Analysis	Laboratory applications, Lecture, question and answer
6	Literature review, homework	Fundamentals of Clinical Biochemistry: Bloodletting, Biochemical Analysis, Metabolism Analysis, Lipid Analysis	Laboratory applications, Lecture, question and answer
7	Literature review, homework	Fundamentals of Clinical Biochemistry: Bloodletting, Biochemical Analysis, Metabolism Analysis, Porphyrin and Heme Metabolism Disorders	Laboratory applications, Lecture, question and answer
8	-	MID-TERM EXAM	-
9	Literature review, homework	Hormone Analysis	Laboratory applications, Lecture, question and answer
10	Literature review, homework	Water Electrolyte Metabolism, Acid-Base Balance and Blood Gases	Laboratory applications, Lecture, question and answer
11	Literature review, homework	Pediatric Laboratory, Pregnancy Biochemistry and Aging Biochemistry and Laboratory Applications	Laboratory applications, Lecture, question and answer
12	Literature review, homework	Metabolism Analysis; Liver Function Tests	Laboratory applications, Lecture, question and answer
13	Literature review, homework	Metabolism Analysis; Kidney Function Tests and Urine Analysis	Laboratory applications, Lecture, question and answer
14	Literature review, homework	Metabolism Analysis; Body fluids	Laboratory applications, Lecture, question and answer
15	Literature review, homework	Metabolism Analysis; Cancer Tumor Markers	Laboratory applications, Lecture, question and answer
16	-	FINAL EXAM	-
17	-	FINAL EXAM	-

SOURCE MATERIALS & RECOMMENDED READING
Konukoğlu, D. (2019). Temel ve Klinik Biyokimya. İstanbul: Nobel Tıp Kitabevleri
Can, M. Güven, B. Demirtaş S. (2018). Tıbbi Biyokimya ve Laboratuvar. İstanbul: Nobel Tıp Kitabevleri
Lieberman, M., & Marks, A. D. (2009). Marks' basic medical biochemistry: a clinical approach. Lippincott Williams & Wilkins.

ASSESSMENT
Assessment & Grading of In-Term Activities	Number of Activities	Degree of Contribution (%)	Description	Examination Method
Mid-Term Exam	1	50
Final Exam	1	50
TOTAL	2	100

Level of Contribution
0	1	2	3	4	5

KNOWLEDGE
Theoretical
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	In the field of Medical Laboratory Techniques Program, is based on theoretical knowledge.						5
2	Required for applications related to the field of methods, techniques and technologies by identifying the services to use effectively.						5
3	Gains information about courses outside the field.	0

KNOWLEDGE
Factual
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Uses the basic knowledge and skills acquired in the field.						5

SKILLS
Cognitive
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Can choose modern techniques, tools and information technologies required for applications related to the field.						5
2	May have knowledge and skills regarding the acquisition and preservation of diagnostic data related to the field.						5

SKILLS
Practical
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Required for applications related to the field of modern techniques, tools and informatics technologies to be able to select and use effectively.						5
2	Can use modern techniques, tools and information technologies required for applications related to the field.						5

OCCUPATIONAL
Autonomy & Responsibility
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Can do individual work in her/his field.						5
2	Can produce solutions when faced with unforeseen situations in applications related to her/his field.						5

OCCUPATIONAL
Learning to Learn
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Gains awareness of the necessity of lifelong learning.						5

OCCUPATIONAL
Communication & Social
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Colleagues, physicians and patients communicate effectively with the ethical framework.						5
2	Examines on-site processes related to its field in public and private sector organizations.						5

OCCUPATIONAL
Occupational and/or Vocational
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Taking material from the patient for testing, storage and transfer shows sufficient skills.						5
2	Uses materials in the medical laboratory in accordance with their techniques.						5
3	Maintains equipment in the medical laboratory in accordance with its techniques.						5
4	Gains the ability to use computers at the basic level required by the field.						5
5	Have knowledge of labor law and occupational safety, environmental protection and quality awareness.						5

WORKLOAD & ECTS CREDITS OF THE COURSE UNIT
Workload for Learning & Teaching Activities
Type of the Learning Activites	Learning Activities (# of week)	Duration (hours, h)	Workload (h)
Lecture & In-Class Activities	14	2	28
Preliminary & Further Study	14	2	28
Land Surveying	0	0	0
Group Work	0	0	0
Laboratory	14	2	28
Reading	0	0	0
Assignment (Homework)	0	0	0
Project Work	0	0	0
Seminar	0	0	0
Internship	0	0	0
Technical Visit	0	0	0
Web Based Learning	0	0	0
Implementation/Application/Practice	0	0	0
Practice at a workplace	0	0	0
Occupational Activity	0	0	0
Social Activity	0	0	0
Thesis Work	0	0	0
Field Study	0	0	0
Report Writing	0	0	0
Final Exam	1	1	1
Preparation for the Final Exam	1	10	10
Mid-Term Exam	1	1	1
Preparation for the Mid-Term Exam	1	10	10
Short Exam	0	0	0
Preparation for the Short Exam	0	0	0
TOTAL	46	0	106