GENEL HİSTOTEKNOLOJİ PROGRAMME COURSE DESCRIPTION

Code	Name of the Course Unit	Semester	In-Class Hours (T+P)	Credit	ECTS Credit
PLP152	GENEL HİSTOTEKNOLOJİ	2	4	2	7

GENERAL INFORMATION
Language of Instruction :	Turkish
Level of the Course Unit :	ASSOCIATE DEGREE, TYY: + 5.Level, EQF-LLL: 5.Level, QF-EHEA: Short Cycle
Type of the Course :	Compulsory
Mode of Delivery of the Course Unit	-
Coordinator of the Course Unit	Assist.Prof. ARZU KAYA KOÇDOĞAN
Instructor(s) of the Course Unit	Assist.Prof. ONUR DİRİCAN
Course Prerequisite	No

OBJECTIVES AND CONTENTS
Objectives of the Course Unit:	Learning pathology procedures, histochemistry techniques, and the stages of preparing specimens for pathological examination, and knowing the techniques.
Contents of the Course Unit:	Learn the pathology laboratory workflow, procedures, specimen collection, fixation, macroscopic examination, sampling, tissue tracking, embedding, sectioning and microtomes, staining and mounting in detail, as well as liquid material preparation procedures.

KEY LEARNING OUTCOMES OF THE COURSE UNIT (On successful completion of this course unit, students/learners will or will be able to)
Applies occupational health and safety rules in the pathology laboratory and works in accordance with laboratory discipline.
Recognizes the basic types of microscopes used in the pathology laboratory and applies the principles of correct use.
Explains the pathology laboratory workflow and quality standards and applies sample acceptance criteria.
Prepares and uses solutions and reagents used in pathology according to their purposes and chemical properties.
Performs macroscopy procedures in accordance with basic rules.
Applies fixation and decalcification procedures according to tissue type.
Uses the tissue tracking device correctly and explains the tracking mechanisms.
Embeds different tissue types using the tissue embedding device according to appropriate embedding principles.
Takes paraffin and frozen sections using a microtome and evaluates section quality.
Defines the characteristics of the sections taken and selects appropriate sectioning techniques.
Correctly performs histological staining procedures (routine and special stains).
Considers the properties of stains and staining activities during the application process.
Performs post-staining sealing and archiving procedures in accordance with laboratory standards.
Applies quality control principles during histotechnological procedures.
Uses applied histotechnology knowledge safely and effectively in the laboratory environment.

WEEKLY COURSE CONTENTS AND STUDY MATERIALS FOR PRELIMINARY & FURTHER STUDY
Week	Preparatory	Topics(Subjects)	Method
1	Preliminary Preparation - Literature review, research.	Pathology Laboratory Safety, Disciplines, and Microscope Introduction	Method - Topic presentation, question-and-answer session.
2	Preliminary Preparation - Literature review, research.	Pathology Laboratory Safety, Disciplines, and Microscope Introduction	Method - Topic presentation, question-and-answer session.
3	Preliminary Preparation - Literature review, research.	Pathology Workflow, Quality Standards, and Sample Acceptance Criteria	Method - Topic presentation, question-and-answer session.
4	Preliminary Preparation - Literature review, research.	Pathology Workflow, Quality Standards, and Sample Acceptance Criteria	Method - Topic presentation, question-and-answer session.
5	Preliminary Preparation - Literature review, research.	Solutions, Solutions Used in Pathology and Their Properties, Macroscopy, Fixation, and Decalcification	Method - Topic presentation, question-and-answer session.
6	Preliminary Preparation - Literature review, research.	Solutions, Solutions Used in Pathology and Their Properties, Macroscopy, Fixation, and Decalcification	Method - Topic presentation, question-and-answer session.
7	Preliminary Preparation - Literature review, research.	Solutions, Solutions Used in Pathology and Their Properties, Macroscopy, Fixation, and Decalcification	Method - Topic presentation, question-and-answer session.
8	Preliminary Preparation - Literature review, research.	Tissue Tracking Device, properties of solutions, tracking mechanisms	Method - Topic presentation, question-and-answer session.
9	Preliminary Preparation - Literature review, research.	Tissue Tracking Device, properties of solutions, tracking mechanisms	Method - Topic presentation, question-and-answer session.
10	-	MID-TERM EXAM	-
11	Preliminary Preparation - Literature review, research.	Tissue Embedding Device, How Different Tissues Are Embedded, and Embedding Principles	Method - Topic presentation, question-and-answer session.
12	Preliminary Preparation - Literature review, research.	Microtome and Sectioning, Section Properties, Frozen Sectioning	Method - Topic presentation, question-and-answer session.
13	Preliminary Preparation - Literature review, research.	Microtome and Sectioning, Section Properties, Frozen Sectioning	Method - Topic presentation, question-and-answer session.
14	Preliminary Preparation - Literature review, research.	Staining, characteristics and activities of stains, sealing and archiving	Method - Topic presentation, question-and-answer session.
15	Preliminary Preparation - Literature review, research.	General Review	Method - Topic presentation, question-and-answer session.
16	-	FINAL EXAM	-
17	-	FINAL EXAM	-

SOURCE MATERIALS & RECOMMENDED READING
Alp Usubütün, (2017) Patoloji Laboratuvarını Anlama Kılavuzu, Ankara Nobel Tıp Kitabevleri
Prof.Dr. Ufuk Usta, Patoloji Laboratuvar Teknikleri Ve Laboratuvar Yönetimi, ISBN: 978-605-80509-4-5
Prof. Dr. Rıfkı Hazıroğlu, Temel Veteriner Patoloji, ISBN: 978-975-06-0985-5

ASSESSMENT
Assessment & Grading of In-Term Activities	Number of Activities	Degree of Contribution (%)	Description	Examination Method
Final Exam	1	100		Computer-Lab-Practice Exam
TOTAL	1	100

Level of Contribution
0	1	2	3	4	5

KNOWLEDGE
Theoretical
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Defines professional responsibility issues such as ethical principles, respect for patients and patient specimens, biosafety of biological samples, and data confidentiality.						5
2	Has basic knowledge of current pathology practices, relevant literature, and emerging technologies (e.g., tissue banking, immunohistochemistry, and molecular pathology) and demonstrates awareness of lifelong learning.						5
3	Plans professional duties in accordance with time management principles.					4

KNOWLEDGE
Factual
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Defines the basic concepts, terminology, and theoretical knowledge used in pathology laboratories.					4
2	Explains tissue processing, fixation, embedding, microtome sectioning, staining, histochemistry, and microscopic examination techniques together with their underlying theoretical principles.					4
3	Has knowledge of laboratory quality control, quality assurance, accreditation standards, biosafety, hygiene, and sterilization principles.						5
4	Explains the characteristics and principles of use of equipment, materials, and chemicals used in pathology laboratories.					4

SKILLS
Cognitive
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Differentiates between normal tissues and pathological structures and provides basic interpretations while evaluating tissues using a microscope.					4
2	Identifies chemical, biological, and physical risks and performs basic risk management.					4
3	Solves basic problems encountered in professional processes by applying analytical thinking.						5

SKILLS
Practical
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Performs fixative preparation, tissue processing, embedding, microtome sectioning, and paraffin section–microscopic slide preparation in the pathology laboratory.						5
2	Performs laboratory procedures such as staining, histochemistry, immunohistochemistry, special staining techniques, and microscopic examination accurately and safely.					4
3	Appropriately manages the use, maintenance, and safety procedures of laboratory equipment (e.g., microtome, microscope, stainer).					4
4	Contributes to sample tracking and result reporting processes by maintaining laboratory records and accurately performs sample coding and data management.					4
5	Complies with biosafety and occupational health and safety regulations while adhering to laboratory quality control procedures.						5
6	Shares professional knowledge and findings accurately and effectively within a team.					4
7	The student develops preventive approaches to creating safe working environments in terms of occupational health.					4

OCCUPATIONAL
Autonomy & Responsibility
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Carries out professional duties and responsibilities independently.					4

OCCUPATIONAL
Learning to Learn
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Is open to continuous professional development and lifelong learning; follows the scientific literature and is willing to learn new techniques.					4

OCCUPATIONAL
Communication & Social
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Communicates effectively with physicians, pathologists, nurses, and laboratory staff, demonstrating openness to teamwork and interdisciplinary collaboration.					4
2	Takes professional responsibility, uses initiative, and demonstrates problem-solving skills when necessary.						5

OCCUPATIONAL
Occupational and/or Vocational
	Programme Learning Outcomes	Level of Contribution
		0	1	2	3	4	5
1	Demonstrates behaviors that prioritize laboratory safety and biosafety at all times, while complying with ethical and professional conduct principles and maintaining patient and specimen confidentiality.						5
2	Takes responsibility for time management, laboratory organization, and work planning, and performs procedures in accordance with standards, accurately, and on time.					4
3	Is aware of legal regulations related to the field, patient rights, biosafety standards, and ethical rules, and complies with these regulations.					4

WORKLOAD & ECTS CREDITS OF THE COURSE UNIT
Workload for Learning & Teaching Activities
Type of the Learning Activites	Learning Activities (# of week)	Duration (hours, h)	Workload (h)
Lecture & In-Class Activities	0	0	0
Preliminary & Further Study	0	0	0
Land Surveying	0	0	0
Group Work	0	0	0
Laboratory	0	0	0
Reading	0	0	0
Assignment (Homework)	0	0	0
Project Work	0	0	0
Seminar	0	0	0
Internship	0	0	0
Technical Visit	0	0	0
Web Based Learning	0	0	0
Implementation/Application/Practice	0	0	0
Practice at a workplace	0	0	0
Occupational Activity	0	0	0
Social Activity	0	0	0
Thesis Work	0	0	0
Field Study	0	0	0
Report Writing	0	0	0
Final Exam	0	0	0
Preparation for the Final Exam	0	0	0
Mid-Term Exam	0	0	0
Preparation for the Mid-Term Exam	0	0	0
Short Exam	0	0	0
Preparation for the Short Exam	0	0	0
TOTAL	0	0	0